What are the key design considerations for liquid rocket turbopumps?

Turbopump design considerations include: Propellant properties (cryogenic handling, density, NPSH requirements), Inducer design for cavitation suppression at low inlet pressures, Impeller design for required head rise (centrifugal or axial), Turbine type (gas generator, expander, staged combustion cycle), Bearing systems (hydrostatic using propellant, ball bearings for lower speed), Seal design to prevent propellant mixing, Rotordynamics for avoiding critical speeds, and Structural integrity under high speed/temperature. Performance requirements: Chamber pressure determines pump discharge pressure (200-500 bar typical), Flow rate sets power requirements (thousands of horsepower). RS-25 SSME turbopumps deliver 70,000 HP at 37,000 RPM. Turbopump failures have caused many rocket failures historically.