DNA Sequence File Formats | Biotechnology Interview | Skill-Lync Resources
Easy Bioinformatics Sequence Analysis

What are the common file formats used to store DNA sequences?

Answer

Common DNA sequence file formats include: FASTA (simple text format with header line starting with > followed by sequence), GenBank/EMBL (annotated format with features, references, and metadata), FASTQ (includes quality scores for each base, used in NGS data), SAM/BAM (Sequence Alignment Map format for aligned sequences, BAM is binary compressed version), VCF (Variant Call Format for genetic variations), and GFF/GTF (Gene Feature Format for annotations). FASTA is the most universal format for basic sequence storage and analysis.

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