What is the difference between monocoque and body-on-frame construction?

Monocoque (unibody) construction integrates the body and frame into a single structure where body panels contribute to overall rigidity. It offers better handling, lighter weight, and more efficient packaging for passenger cars. Body-on-frame has a separate ladder frame supporting the body, offering higher load capacity, easier repair, and durability for trucks and SUVs. Most modern cars use monocoque, while pickup trucks and off-road vehicles often use body-on-frame.